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NITRO-TYROSINE DETECTION

Nitration of tyrosine residues occurs in various cell types and depends mainly, in vivo or in vitro, on the formation of peroxynitrite from singulet oxygen and nitric oxyde.

Nitration of tyrosine residues in proteins could interfere with many transduction pathways since nitration of tyrosine residues prevents phosphorylation of this amino-acid and therefore its recognition by specific motifs.

Nitration is so one of causes of physiological process like inflammation, immune response and atherosclerosis.

Rb IgG anti-nitrotyrosine containing peptides Immunoaffinity Column

Application: interesting for the screening of nitrotyrosine containing peptides

Matrix: SepharoseTM 4 Fast Flow.
Spacer arm: 12 atoms.
Ligand: Rabbit IgG anti-nitrotyrosine containing peptides.
Attachment: at Fc portion of IgG.
Immobilized ligand: 10,000 g of Rb IgG per ml of resin.
Affinity resin volume: 400 l wet resin.
Specificity: determined by RIA - 4 g of nitrotyrosine containing peptides per 400 l of resin column.
Storage: 4C, suspension in PBS buffer, pH 7.4, in the presence of NaN3 0.1% (w/v).

ORDERING INFORMATION

Product code Product name Quantity *Price in EUR
Rb IgG-NT-c Rabbit IgG anti-nitrotyrosine containing peptide column 1 ea 365.00
5 ea 1734.00
> 10 ea Please inquire
Rb IgG-NT-a Rabbit IgG anti-nitrotyrosine containing peptide antibody 1000 g 149.00
* All prices are FOB Liège.
Bulk quantities are available.

Shipment at room temperature


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